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John W. Gamel, MD; Richard A. Eiferman, MD; Pierre Guibor, MD

Arch Ophthalmol. 1984;102(5):730-731.

Abstract
• A 73-year-old man had a limbal nodule that, on histopathologic examination, proved to be mucoepidermoid carcinoma of the conjunctiva. Despite radiation therapy and extensive corneoscleral lamellar resection, widespread invasion of the lids and orbit ultimately led to exenteration. Although mucoepidermoid carcinoma of the conjunctiva resembles squamous cell carcinoma clinically and histopathologically, it pursues a more rapid and destructive clinical course. Intraepithelial invasion often leads to tumor involvement of conjunctiva and skin that seem normal on clinical examination. Special stains and a high level of suspicion are required for diagnosis of mucoepidermoid carcinoma of the conjunctiva, and proper initial management demands more aggressive surgical resection than is usually indicated for squamous cell carcinoma.

Author Affiliations
From the Veterans Administration Hospital, Louisville (Dr Eiferman), the Department of Ophthalmology, University of Louisville School of Medicine (Drs Gamel and Eiferman), and the Manhattan Eye, Ear, and Throat Hospital, New York (Dr Guibor).

Footnotes
Accepted for publication Dec 23, 1983.

Reprint requests to Department of Ophthalmology, University of Louisville School of Medicine, 301 E Muhammad Ali Blvd, Louisville, KY 40202 (Dr Gamel).

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