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John R. Thompson, PhD; John M. Sparrow, DPhil, FRCS; Jonathan M. Gibson, MD, FRCS; A. Ralph Rosenthal, MD, FCOphth

Arch Ophthalmol. 1993;111(5):675-679.

Abstract
• Follow-up ranging between 6 and 8 years of the survival of a cohort of 473 elderly nondiabetic subjects randomly selected from a small English town showed an age- and sex-adjusted association between nuclear cataract at the time of baseline examination and decreased survival (P=.002). Comparing those with and without nuclear cataract, the adjusted relative hazard for death was 1.52 (95% confidence interval, 1.15 to 1.99). This effect remained virtually unchanged when also adjusted for whether the subject reported ever having been a smoker.

Author Affiliations
From the Department of Ophthalmology, University of Leicester (England) (Drs Thompson, Sparrow, and Rosenthal), and Birmingham and Midland Eye Hospital, Birmingham, England (Dr Gibson). Dr Sparrow is now with the University of Bristol (England).

Footnotes
Accepted for publication December 11, 1992.

Reprint requests to Department of Ophthalmology, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, PO Box 65, Leicester LE2 7LX, England (Dr Thompson).

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