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Ocular Reticulum Cell SarcomaPresentation as Retinal Detachment With Demonstration of Monoclonal Immunoglobulin Light Chains on the Vitreous Cells
Joseph B. Michelson, MD;
Paul E. Michelson, MD;
Gerald M. Bordin, MD;
Francis V. Chisari, MD
Arch Ophthalmol. 1981;99(8):1409-1411.
Abstract
• A 61-year-old man with a history of cerebral reticulum cell sarcoma-microglioma (histiocytic lymphoma) in remission was initially seen with uveitis and exudative retinal detachment. Pars plana vitreous biopsy established the diagnosis by cytologic findings and allowed the immunofluorescent demonstration of a monoclonal immunoglobulin within the vitreous cells. Direct immunofluorescent microscopy of the vitreous infiltrate may prove to be of benefit in the workup of patients with uveitis in whom malignant lymphoma must be excluded.
Author Affiliations
From the Division of Ophthalmology (Drs J. Michelson and P. Michelson) and the Department of Clinical Pathology (Drs Bordin and Chisari), Scripps Clinic and Research Foundation, La Jolla, Calif.
Footnotes
Accepted for publication Sept 8, 1980.
Reprint requests to the Division of Ophthalmology, Scripps Clinic and Research Foundation, 10666 N Torrey Pines Rd, La Jolla, CA 92037 (Dr J. Michelson).
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