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Bilateral Sporadic Retinoblastoma in a Child Born After In Vitro Fertilization
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In the October 2001 issue of the ARCHIVES, Anteby et al1 described the ocular abnormalities found in children born after in vitro fertilization (IVF), including 1 case of unilateral retinoblastoma.
In January 2001, we saw a case of sporadic bilateral retinoblastoma in a child born after IVF. A 3-year-old girl was referred because of strabismus of the left eye. There was no family history of ocular disorders. On ocular examination, visual acuity was 20/20 OD and less than 20/1000 OS. External examination showed exotropia of the left eye with a small angle of squint. Anterior segments were normal. On ophthalmoscopic examination, a small retinoblastoma was found at the nasal periphery of the right eye, and a very large retinoblastoma was found at the posterior pole of the left eye. Intratumoral calcification was established with ultrasonography. Histopathologic analysis of the enucleated left eye confirmed the diagnosis of retinoblastoma. The tumor in . . . [Full Text of this Article]
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