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Arch Ophthalmol. 2005;123:1750-1754.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Though infrequently encountered by most ophthalmologists, optic nerve pits and optic nerve colobomas (typical and atypical) are well known cavitary optic disc anomalies.^1-2 Maculopathy characterized by macular schisis, outer layer detachments, and occasionally outer layer holes are frequently associated with cavitary optic disc anomalies.^{1, 3-4} The etiology of the maculopathy and source of the subretinal fluid are unknown but both systemic and intraocular factors have been proposed.^3-9

Fluctuations, and even spontaneous resolution, of the described maculopathy can occur but are uncommon.^{1, 3, 5, 10} Though other cavitary optic disc anomalies have rarely been reported to fluctuate in appearance,^11-13 we are unaware of any previous reports of fluctuating optic pits or atypical colobomas. We present 3 unique cases in which the fluctuating appearance of an atypical optic nerve coloboma is associated with spontaneous resolution of the associated maculopathy.

Report of Cases

Case 1. A 40-year-old white woman sought care because of a 1-week history of decreased vision in . . . [Full Text of this Article]

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AUTHOR INFORMATION
Stephen L. Perkins, MD; Dennis P. Han, MD; John R. Gonder, MD; Paul E. Beaumont, MBBS, FRACO, FRACS; George Colev, FRCS

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