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I was intrigued by Dr Higginbotham’s editorial "Does Sex Matter in Glaucoma?"¹ If there is indeed a connection between sex and, specifically, age at onset of menopause with the development of open-angle glaucoma, might it not be worthwhile to further the comparison with the onset of menarche? I would postulate that the total exposure to endogenous estrogen in a woman’s lifetime, from onset to cessation, rather than cessation alone might prove to be the critical variable.

It was a thoughtful and thought-provoking editorial.

AUTHOR INFORMATION
Correspondence: Ms Podos, Department of Ophthalmology, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1183, New York, NY 10029-6574 (steven.podos@mssm.edu).

Wendy Donn Podos, MPH

1. Higginbotham EJ. Does sex matter in glaucoma? Arch Ophthalmol. 2004;122:374-375. FREE FULL TEXT

Arch Ophthalmol. 2005;123:284.

RELATED ARTICLE

Sex Matters in Glaucoma—Reply
Eve J. Higginbotham
Arch Ophthalmol. 2005;123(2):284.
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