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Choroidal Infarction Following Photodynamic Therapy With Verteporfin
Arch Ophthalmol. 2005;123:1149-1153.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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In recent years, photodynamic therapy (PDT) using verteporfin has emerged as an important method for treating certain subtypes of choroidal neovascularization (CNV) in age-related macular degeneration.1 Despite the significant beneficial effects, a 4% risk of acute severe vision decrease has been reported for patients undergoing PDT with verteporfin.2 An initial thermally enhanced photochemical impact on the macula appears to induce changes in the choriocapillaris to arrest the progression of the neovascularized complex without significant permanent damage to the choriocapillaris, retinal pigment epithelium, and photoreceptors.3 There have been a few cases, however, of transient choroidal ischemia, where normal choroidal vessels have shown evidence of transient delay. The ischemic change in these eyes evolves without clinical evidence of permanent damage. This is a report of a choroidal infarction observed in the treatment of CNV in age-related macular degeneration using standard methods of PDT with verteporfin.
Report of Cases
Case 1. In an otherwise healthy . . . [Full Text of this Article] Comment
AUTHOR INFORMATION
Christina M. Klais, MD;
Michael D. Ober, MD;
K. Bailey Freund, MD;
Leonard H. Ginsburg, MD;
Alan Luckie, MD;
Martine Mauget-Faÿsse, MD;
Gabriel Coscas, MD;
Nicole E. Gross, MD;
Lawrence A. Yannuzzi, MD
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