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Tamoxifen-Induced Regression of a Choroidal Metastasis in a Man
Arch Ophthalmol. 2005;123:1153-1154.
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We present a case of chemotherapeutic regression of a metastatic breast carcinoma to the choroid in a male patient. The rapid response to systemic tamoxifen prevented the patient from receiving local radiotherapy and helped confirm the suspected diagnosis of a choroidal metastasis.
Report of a Case
A 76-year-old man was referred with an inferior field defect. Right funduscopy revealed a solitary, pale, elevated choroidal mass underlying the superior temporal arcade (Figure 1). The mass was 3.7 mm high with a maximum basal diameter of 6.8 mm. The lesion showed low internal reflectivity on ocular ultrasound. No choroidal lesions were seen in the left fundus. The differential diagnosis was either an amelanotic melanoma or a metastatic deposit. He was investigated for metastatic disease prior to planned treatment with ruthenium plaque brachytherapy.
Figure appears in full text version.
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Figure 1. A color fundus photograph of a pale, elevated choroidal mass underlying the right superior temporal vascular arcade.
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A shadow was . . . [Full Text of this Article] Comment
AUTHOR INFORMATION
Victoria Mary Lendrum Cohen, MD, MRCOphth;
Reza Moosavi, MD, MRCOphth;
John L. Hungerford, MD, FRCS, FRCOphth
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