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Plasmapheresis for Lupus Retinal Vasculitis
Thekla G. Papadaki, MD;
Ioannis P. Zacharopoulos, MD;
George Papaliodis, MD;
Barbara Iaccheri, MD;
Tito Fiore, MD;
C. Stephen Foster, MD, FACS
Arch Ophthalmol. 2006;124:1654-1656.
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Systemic lupus erythematosus (SLE) is a potentially lethal, chronic autoimmune disease that can involve the eye. It is characterized by the production of numerous autoantibodies, some of which are pathogenic. Retinal vasculitis is the most serious of ocular manifestations; it is potentially blinding and associated with a decreased survival rate.1-2 Immunosuppressive therapy is the mainstay of treatment3 but plasmapheresis can be helpful acutely by rapidly removing circulating immune complexes and immune reactants while the patient is receiving immunomodulators. We present 2 cases of severe retinal vasculitis due to SLE that were treated successfully with a combination of plasmapheresis and immunosuppression.
Report of Cases
Case 1. A 54-year old white woman was admitted because of renal failure and changes in mental status. A month earlier the patient had complained of decreased . . . [Full Text of this Article]
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Arch Ophthalmol 2007;125:1443-1443.
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Lupus Treated With Plasmapheresis
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