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  Vol. 125 No. 11, November 2007 TABLE OF CONTENTS
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  Clinical Trial Retrospective
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The Ischemic Optic Neuropathy Decompression Trial

Nancy J. Newman, MD

Arch Ophthalmol. 2007;125(11):1568-1570.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common cause of acute optic nerve disease in the elderly and often results in severe visual loss.1 The average annual incidence has been estimated at 2.3 to 10.2 per 100 000 persons aged 50 years and older with about 1500 to 6000 new cases seen each year in the United States.2-4 Although the visual acuity in patients with NAION remains better than 20/60 in approximately 50% of affected patients, the visual field is invariably abnormal, and more than one-third of patients have vision worse than 20/200 in the affected eye.5-7 Second eye involvement occurs in approximately 15% to 20% of patients with NAION within 5 years8-9 and often results in a dramatic reduction in patient independence and quality of life.

No therapy for acute NAION or prevention of fellow eye involvement has yet proved to be effective. In . . . [Full Text of this Article]


AUTHOR INFORMATION

RELATED ARTICLE

Lessons From the Ischemic Optic Neuropathy Decompression Trial: A Decade Later
Leonard A. Levin
Arch Ophthalmol. 2007;125(11):1570-1571.
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