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Osteoporosis-Pseudoglioma Syndrome May Not Be Caused by Persistent Fetal Vasculature
Michael P. Blair, MD;
Michael J. Shapiro, MD
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We read with interest the photo essay by Lai et al.1 They show fundus photographs of a patient with osteoporosis-pseudoglioma syndrome to support the development of pseudoglioma from persistent fetal vasculature (PFV). We find the photographic evidence for this questionable.
A review of the figures does not support a primary role for PFV. Part A of their Figure shows a falciform retinal fold extending temporally from the optic disc rather than a fibrotic band. The falciform retinal detachment common in retinopathy of prematurity and familial exudative vitreoretinopathy should be distinguished from the tent-shaped retinal detachment more typical of PFV.2 Furthermore, the arrow points to a retinal blood vessel on the anterior aspect of the fold and not a remnant of the hyaloid artery. Retinal blood vessels are always found at the ridge of falciform folds from peripheral fibrovascular contraction. Finally, there are . . . [Full Text of this Article]
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RELATED LETTER
Osteoporosis-Pseudoglioma Syndrome May Not Be Caused by Persistent Fetal Vasculature—Reply
Timothy Y. Y. Lai
Arch Ophthalmol. 2007;125(3):433.
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