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Highly Active Antiretroviral Therapy–Associated Ptosis in Patients With Human Immunodeficiency Virus
Rona Z. Silkiss, MD;
Han Lee, MD, PhD;
Vincent L. Gills Ray, MD
Arch Ophthalmol. 2009;127(3):345-346.
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We describe 2 patients with human immunodeficiency virus (HIV)/AIDS receiving highly active antiretroviral therapy with bilateral ptosis. In both cases, the ptosis developed during the course of the disease and its treatment. Each patient underwent surgical ptosis repair. A biopsy of the advanced levator complex, including the levator muscle, aponeurosis, and orbicularis oculi muscle, was obtained intraoperatively. This was compared with a similar biopsy taken from an HIV-negative control subject.
Report of Cases
Case 1
A 57-year-old man with a medical history of HIV/AIDS was referred for treatment of vision-impairing upper eyelid ptosis. He was treated for cytomegalovirus retinitis in his left eye 15 years prior to his initial visit to us. His HIV medications included lamivudine (Epivir; GlaxoSmithKline, Philadelphia, Pennsylvania) and didanosine (Videx; Bristol-Myers Squibb Co, New York, New York), both of which are nucleoside analogues similar to zidovudine, as well . . . [Full Text of this Article] Case 2 Comment
AUTHOR INFORMATION
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