This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Bradley J. Katz, MD, PhD; William E. Scott, MD; James C. Folk, MD
Iowa City, Iowa

Arch Ophthalmol. 1997;115(11):1470-1472.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Ocular infection with the fungus Histoplasma capsulatum may manifest in 2 ways. The first is an acute granulomatous uveitis or panophthalmitis that occurs in immunocompromised hosts. The second manifestation of ocular involvement by H capsulatum, seen in immunocompetent hosts, is the presumed ocular histoplasmosis syndrome (POHS). The syndrome is defined by peripheral atrophic scars, peripapillary atrophy, and choroidal neovascularization in the posterior pole (the "histoplasmosis triad"). It is still debated whether H capsulatum organisms have ever been definitively identified within these scars,¹ and decades may elapse between the initial infection and the development of choroidal neovascularization.² In addition, choroidal scars similar to those associated with POHS may be observed in other disorders. Although substantial epidemiological evidence exists that that there is a causal relationship between POHS and H capsulatum,³ the etiology of POHS remains unproven.

Acute choroidal infection in immunocompetent patients rarely, if ever, comes to the . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?